Molecular profiles of BRCA1-mutated and matched sporadic breast tumours: relation with clinico-pathological features

About 5–10% of breast cancers are hereditary; a genetically and clinically heterogeneous disease in which several susceptibility genes, including BRCA1, have been identified. While distinct tumour features can be used to estimate the likelihood that a breast tumour is caused by a BRCA1 germline muta...

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Veröffentlicht in:	British journal of cancer 2001-08, Vol.85 (4), p.538-545
Hauptverfasser:	Berns, E M J J, Staveren, I L van, Verhoog, L, Ouweland, A M W van de, Gelder, M Meijer-van, Meijers-Heijboer, H, Portengen, H, Foekens, J A, Dorssers, L C J, Klijn, J G M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Research Cell Adhesion Cell Movement DNA Mutational Analysis DNA, Complementary - analysis Drug Resistance Epidemiology Female Gene Expression Regulation Genes, BRCA1 - genetics Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Molecular Medicine Mutation Oligonucleotide Array Sequence Analysis Oncology Ovarian cancer Pathology Regular regular-article RNA - analysis RNA - genetics Tumors
Online-Zugang:	Volltext
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