Identification of a novel spliced variant of the SYT gene expressed in normal tissues and in synovial sarcoma

Synovial sarcoma (SS) is cytogenetically characterized by the translocation t(X;18)(p11.2-q11.2) generating a fusion between the SYT gene on chromosome 18 and one member of the SSX family gene (SSX1; SSX2; SSX4) on chromosome X. Here, we report for the first time that 2 forms of SYT mRNA are present...

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Veröffentlicht in:	British journal of cancer 2001-04, Vol.84 (8), p.1087-1094
Hauptverfasser:	Tamborini, E, Agus, V, Mezzelani, A, Riva, C, Sozzi, G, Azzarelli, A, Pierotti, M A, Pilotti, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Amino acids Base Sequence Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Chromosomes Diseases of the osteoarticular system DNA, Complementary - chemistry DNA, Complementary - genetics Drug Resistance Epidemiology Gene Expression Regulation, Neoplastic Genes Genetic Variation Humans Localization Medical research Medical sciences Metastasis Molecular Medicine Molecular Sequence Data Oncogene Proteins, Fusion - genetics Oncology Pathogenesis Proteins Proteins - genetics Proto-Oncogene Proteins Regular regular-article Repressor Proteins RNA - genetics RNA - metabolism Sarcoma Sarcoma, Synovial - genetics Sarcoma, Synovial - pathology Sequence Alignment Sequence Analysis, DNA Sequence Homology, Nucleic Acid Tissue Distribution Tumor Cells, Cultured Tumors Tumors of striated muscle and skeleton
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