Lactation and breast cancer risk: a case–control study in Connecticut
In this report, we examined the relationship between lactation and breast cancer risk, in a case–control study of breast cancer, conducted in Connecticut between 1994 and 1998. Included were 608 incident breast cancer cases and 609 age frequency matched controls, aged 30–80 years old. Cases and cont...
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| Veröffentlicht in: | British journal of cancer 2001-06, Vol.84 (11), p.1472-1476 |
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| creator | Zheng, T Holford, T R Mayne, S T Owens, P H Zhang, Y Zhang, B Boyle, P Zahm, S H |
| description | In this report, we examined the relationship between lactation and breast cancer risk, in a case–control study of breast cancer, conducted in Connecticut between 1994 and 1998. Included were 608 incident breast cancer cases and 609 age frequency matched controls, aged 30–80 years old. Cases and controls were interviewed by trained study interviewers, using a standardized, structured questionnaire, to obtain information on lactation and other major risk factors. Parous women who reported ever lactation had a borderline significantly reduced risk of breast cancer (OR=0.83, 95% CI, 0.63–1.09). An OR of 0.53 (95% CI, 0.27–1.04) was observed in those having breastfed more than 3 children compared to those who never lactated. Women having breastfed their first child for more than 13 months had an OR of 0.47 (95% CI, 0.23–0.94) compared to those who never breastfed. Lifetime duration of lactation also showed a risk reduction while none of the ORs were statistically significant. Further stratification by menopausal status showed a risk reduction related to lactation for both pre- and postmenopausal women, while the relationship is less consistent for the latter. These results support an inverse association between breastfeeding and breast cancer risk. © 2001 Cancer Research Campaign
http://www.bjcancer.com |
| doi_str_mv | 10.1054/bjoc.2001.1793 |
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http://www.bjcancer.com</description><identifier>ISSN: 0007-0920</identifier><identifier>ISSN: 1532-1827</identifier><identifier>EISSN: 1532-1827</identifier><identifier>DOI: 10.1054/bjoc.2001.1793</identifier><identifier>PMID: 11384096</identifier><identifier>CODEN: BJCAAI</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Breast cancer ; Breast Neoplasms - etiology ; Breast Neoplasms - prevention & control ; Cancer Research ; Case-Control Studies ; Connecticut - epidemiology ; Drug Resistance ; Epidemiology ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Incidence ; Lactation ; Mammary gland diseases ; Medical sciences ; Middle Aged ; Molecular Medicine ; Odds Ratio ; Oncology ; Regular ; regular-article ; Risk Assessment ; Time Factors ; Tumors</subject><ispartof>British journal of cancer, 2001-06, Vol.84 (11), p.1472-1476</ispartof><rights>The Author(s) 2001</rights><rights>2001 INIST-CNRS</rights><rights>Copyright 2001 Cancer Research Campaign.</rights><rights>Copyright Nature Publishing Group Jun 2001</rights><rights>Copyright © 2001 Cancer Research Campaign 2001 Cancer Research Campaign</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c514t-524b81aaea8ba45bebf9daf620988d74a14a25d509a9fc15802e6332a99ed7e33</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363665/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363665/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1085756$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11384096$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zheng, T</creatorcontrib><creatorcontrib>Holford, T R</creatorcontrib><creatorcontrib>Mayne, S T</creatorcontrib><creatorcontrib>Owens, P H</creatorcontrib><creatorcontrib>Zhang, Y</creatorcontrib><creatorcontrib>Zhang, B</creatorcontrib><creatorcontrib>Boyle, P</creatorcontrib><creatorcontrib>Zahm, S H</creatorcontrib><title>Lactation and breast cancer risk: a case–control study in Connecticut</title><title>British journal of cancer</title><addtitle>Br J Cancer</addtitle><addtitle>Br J Cancer</addtitle><description>In this report, we examined the relationship between lactation and breast cancer risk, in a case–control study of breast cancer, conducted in Connecticut between 1994 and 1998. Included were 608 incident breast cancer cases and 609 age frequency matched controls, aged 30–80 years old. Cases and controls were interviewed by trained study interviewers, using a standardized, structured questionnaire, to obtain information on lactation and other major risk factors. Parous women who reported ever lactation had a borderline significantly reduced risk of breast cancer (OR=0.83, 95% CI, 0.63–1.09). An OR of 0.53 (95% CI, 0.27–1.04) was observed in those having breastfed more than 3 children compared to those who never lactated. Women having breastfed their first child for more than 13 months had an OR of 0.47 (95% CI, 0.23–0.94) compared to those who never breastfed. Lifetime duration of lactation also showed a risk reduction while none of the ORs were statistically significant. Further stratification by menopausal status showed a risk reduction related to lactation for both pre- and postmenopausal women, while the relationship is less consistent for the latter. These results support an inverse association between breastfeeding and breast cancer risk. © 2001 Cancer Research Campaign
http://www.bjcancer.com</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - etiology</subject><subject>Breast Neoplasms - prevention & control</subject><subject>Cancer Research</subject><subject>Case-Control Studies</subject><subject>Connecticut - epidemiology</subject><subject>Drug Resistance</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Incidence</subject><subject>Lactation</subject><subject>Mammary gland diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Molecular Medicine</subject><subject>Odds Ratio</subject><subject>Oncology</subject><subject>Regular</subject><subject>regular-article</subject><subject>Risk Assessment</subject><subject>Time Factors</subject><subject>Tumors</subject><issn>0007-0920</issn><issn>1532-1827</issn><issn>1532-1827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kUFrFDEYhoModq1ePcogoqfZfkkmM4kHQRatwoIXPYdvMpmadTapSUbozf_Qf9hfYoZdbBX0FD7y5M2bPIQ8pbCmIJqzfhfMmgHQNe0Uv0dWVHBWU8m6-2QFAF0NisEJeZTSrowKZPeQnFDKZQOqXZHzLZqM2QVfoR-qPlpMuTLojY1VdOnb6wrLmOzNz2sTfI5hqlKeh6vK-WoTvLcmOzPnx-TBiFOyT47rKfny_t3nzYd6--n84-bttjaCNrkWrOklRbQoe2xEb_tRDTi2DJSUQ9cgbZCJQYBCNRoqJDDbcs5QKTt0lvNT8uaQezn3ezsYWyrhpC-j22O80gGd_nPHu6_6IvzQjLe8bUUJeHUMiOH7bFPWe5eMnSb0NsxJS6Uoh041hXz5X7IDKRlrl07P_wJ3YY6-fINmTKlWMJAFWh8gE0NK0Y6_O1PQi0q9qNSLSr2oLAee3X3pLX50V4AXRwCTwWmMRZpLd2Kl6MSCnR2wVHb8hY237f5x8y_pl7eK</recordid><startdate>20010601</startdate><enddate>20010601</enddate><creator>Zheng, T</creator><creator>Holford, T R</creator><creator>Mayne, S T</creator><creator>Owens, P H</creator><creator>Zhang, Y</creator><creator>Zhang, B</creator><creator>Boyle, P</creator><creator>Zahm, S H</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope><scope>5PM</scope></search><sort><creationdate>20010601</creationdate><title>Lactation and breast cancer risk: a case–control study in Connecticut</title><author>Zheng, T ; Holford, T R ; Mayne, S T ; Owens, P H ; Zhang, Y ; Zhang, B ; Boyle, P ; Zahm, S H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c514t-524b81aaea8ba45bebf9daf620988d74a14a25d509a9fc15802e6332a99ed7e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - etiology</topic><topic>Breast Neoplasms - prevention & control</topic><topic>Cancer Research</topic><topic>Case-Control Studies</topic><topic>Connecticut - epidemiology</topic><topic>Drug Resistance</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Incidence</topic><topic>Lactation</topic><topic>Mammary gland diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Molecular Medicine</topic><topic>Odds Ratio</topic><topic>Oncology</topic><topic>Regular</topic><topic>regular-article</topic><topic>Risk Assessment</topic><topic>Time Factors</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zheng, T</creatorcontrib><creatorcontrib>Holford, T R</creatorcontrib><creatorcontrib>Mayne, S T</creatorcontrib><creatorcontrib>Owens, P H</creatorcontrib><creatorcontrib>Zhang, Y</creatorcontrib><creatorcontrib>Zhang, B</creatorcontrib><creatorcontrib>Boyle, P</creatorcontrib><creatorcontrib>Zahm, S H</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British journal of cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zheng, T</au><au>Holford, T R</au><au>Mayne, S T</au><au>Owens, P H</au><au>Zhang, Y</au><au>Zhang, B</au><au>Boyle, P</au><au>Zahm, S H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lactation and breast cancer risk: a case–control study in Connecticut</atitle><jtitle>British journal of cancer</jtitle><stitle>Br J Cancer</stitle><addtitle>Br J Cancer</addtitle><date>2001-06-01</date><risdate>2001</risdate><volume>84</volume><issue>11</issue><spage>1472</spage><epage>1476</epage><pages>1472-1476</pages><issn>0007-0920</issn><issn>1532-1827</issn><eissn>1532-1827</eissn><coden>BJCAAI</coden><abstract>In this report, we examined the relationship between lactation and breast cancer risk, in a case–control study of breast cancer, conducted in Connecticut between 1994 and 1998. Included were 608 incident breast cancer cases and 609 age frequency matched controls, aged 30–80 years old. Cases and controls were interviewed by trained study interviewers, using a standardized, structured questionnaire, to obtain information on lactation and other major risk factors. Parous women who reported ever lactation had a borderline significantly reduced risk of breast cancer (OR=0.83, 95% CI, 0.63–1.09). An OR of 0.53 (95% CI, 0.27–1.04) was observed in those having breastfed more than 3 children compared to those who never lactated. Women having breastfed their first child for more than 13 months had an OR of 0.47 (95% CI, 0.23–0.94) compared to those who never breastfed. Lifetime duration of lactation also showed a risk reduction while none of the ORs were statistically significant. Further stratification by menopausal status showed a risk reduction related to lactation for both pre- and postmenopausal women, while the relationship is less consistent for the latter. These results support an inverse association between breastfeeding and breast cancer risk. © 2001 Cancer Research Campaign
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| subjects | Adult Aged Biological and medical sciences Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - etiology Breast Neoplasms - prevention & control Cancer Research Case-Control Studies Connecticut - epidemiology Drug Resistance Epidemiology Female Gynecology. Andrology. Obstetrics Humans Incidence Lactation Mammary gland diseases Medical sciences Middle Aged Molecular Medicine Odds Ratio Oncology Regular regular-article Risk Assessment Time Factors Tumors |
| title | Lactation and breast cancer risk: a case–control study in Connecticut |
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