Dose-related nephrotoxicity of carboplatin in children

Summary This study investigated changes and the time course of these changes in renal function in children following treatment with carboplatin, and identified risk factors for nephrotoxicity. Glomerular and proximal renal tubular function were investigated before and up to 2 years after treatment i...

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Veröffentlicht in:	British journal of cancer 1999-09, Vol.81 (2), p.336-341
Hauptverfasser:	English, M W, Skinner, R, Pearson, A D J, Price, L, Wyllie, R, Craft, A W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antineoplastic Agents - adverse effects Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - therapeutic use Area Under Curve Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Carboplatin - adverse effects Carboplatin - pharmacokinetics Carboplatin - therapeutic use Child Child, Preschool Drug Resistance Drug toxicity and drugs side effects treatment Epidemiology Female Glomerular Filtration Rate Humans Infant Kidney Diseases - chemically induced Kidney Function Tests Magnesium - blood Male Medical sciences Molecular Medicine Oncology Pharmacology. Drug treatments Regular regular-article Risk Factors Toxicity: urogenital system
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