A prospective randomised trial to study the role of levamisole and interferon alfa in an adjuvant therapy with 5-FU for stage III colon cancer

The purpose of this trial was to examine the efficacy of the addition of levamisole (LEV) or interferon alfa (IFN) to an adjuvant chemotherapy with 5-fluorouracil (5-FU) in patients with stage III colon cancer. According to a 2 × 2 factorial study design, 598 patients were randomly assigned to one o...

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Veröffentlicht in:	British journal of cancer 2005-05, Vol.92 (9), p.1655-1662
Hauptverfasser:	Schippinger, W, Jagoditsch, M, Sorré, C, Gnant, M, Steger, G, Hausmaninger, H, Mlineritsch, B, Schaberl-Moser, R, Mischinger, H J, Hofbauer, F, Holzberger, P, Mittlböck, M, Jakesz, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Clinical Study Colonic Neoplasms - drug therapy Colonic Neoplasms - surgery Combined Modality Therapy Disease-Free Survival Drug Administration Schedule Drug Resistance Epidemiology Female Fluorouracil - administration & dosage Gastroenterology. Liver. Pancreas. Abdomen Humans Interferon-alpha - administration & dosage Interferon-alpha - adverse effects Leucovorin - administration & dosage Levamisole - administration & dosage Male Medical sciences Middle Aged Molecular Medicine Neoplasm Recurrence, Local Oncology Prognosis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Survival Analysis Tumors
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