Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer

Tumour hypoxia is a microenvironmental factor related to poor response to radiation, chemotherapy, genetic instability, selection for resistance to apoptosis, and increased risk of invasion and metastasis. Hypoxia-regulated carbonic anhydrase IX (CA IX) has been studied in various tumour sites and i...

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Veröffentlicht in:	British journal of cancer 2007-01, Vol.96 (1), p.104-109
Hauptverfasser:	Hussain, S A, Ganesan, R, Reynolds, G, Gross, L, Stevens, A, Pastorek, J, Murray, P G, Perunovic, B, Anwar, M S, Billingham, L, James, N D, Spooner, D, Poole, C J, Rea, D W, Palmer, D H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - chemistry Apoptosis Biological and medical sciences Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - chemistry Biomedical and Life Sciences Biomedicine Biopsy Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - metabolism Breast Neoplasms - surgery Cancer Research Cancer therapies Carbonic Anhydrase IX Carbonic Anhydrases - biosynthesis Carbonic Anhydrases - chemistry Chemotherapy Clinical outcomes Data Interpretation, Statistical Drug Resistance Epidemiology Female Follow-Up Studies Gynecology. Andrology. Obstetrics Humans Hypoxia Immunohistochemistry Laboratories Mammary gland diseases Medical research Medical sciences Metastasis Middle Aged Molecular Diagnostics Molecular Medicine Neoplasm Invasiveness Neoplasm Staging Oncology Patients Predictive Value of Tests Prognosis Radiation Retrospective Studies Staining and Labeling Survival Rate Tissue Array Analysis - methods Tumors
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