Conditionally Replicating Mycobacteriophages: A System for Transposon Delivery to Mycobacterium tuberculosis

Transposon mutagenesis provides a direct selection for mutants and is an extremely powerful technique to analyze genetic functions in a variety of prokaryotes. Transposon mutagenesis of Mycobacterium tuberculosis has been limited in part because of the inefficiency of the delivery systems. This repo...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1997-09, Vol.94 (20), p.10961-10966
Hauptverfasser:	Bardarov, Stoyan, Kriakov, Jordan, Carriere, Christian, Yu, Shengwei, Vaamonde, Carlos, McAdam, Ruth A., Bloom, Barry R., Hatfull, Graham F., Jacobs, William R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteriophages Biological Sciences Cosmids DNA Transposable Elements Genetic transposition Genetic Vectors Infections Libraries Medical research Microbiology Mutagenesis Mycobacteriophages Mycobacteriophages - genetics Mycobacteriophages - physiology Mycobacterium - growth & development Mycobacterium - virology Mycobacterium tuberculosis Species Specificity Transposons Tuberculosis Virus Replication - genetics
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