Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice

The physiological significance of the presence of GLUT2 at the food-facing pole of intestinal cells is addressed by a study of fructose absorption in GLUT2-null and control mice submitted to different sugar diets. Confocal microscopy localization, protein and mRNA abundance, as well as tissue and me...

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Veröffentlicht in:	The Journal of physiology 2003-11, Vol.552 (3), p.823-832
Hauptverfasser:	Gouyon, F., Caillaud, L., Carrière, V., Klein, C., Dalet, V., Citadelle, D., Kellett, G. L., Thorens, B., Leturque, A., Brot‐Laroche, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Dietary Sucrose - pharmacology Enterocytes - metabolism Fructose - administration & dosage Fructose - pharmacokinetics Glucose - administration & dosage Glucose Transporter Type 2 Glucose Transporter Type 5 Intestinal Absorption Intestines - metabolism Membrane Glycoproteins - metabolism Mice Mice, Knockout Microvilli - metabolism Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism Original Sodium-Glucose Transporter 1 Tissue Distribution
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