Cardiovascular and endocrine responses to acute hypoxaemia during and following dexamethasone infusion in the ovine fetus

This study investigated the effects of fetal treatment with dexamethasone on ovine fetal cardiovascular defence responses to acute hypoxaemia, occurring either during or 48 h following the period of glucocorticoid exposure. To address the mechanisms underlying these responses, chemoreflex function a...

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Veröffentlicht in:	The Journal of physiology 2003-05, Vol.549 (1), p.271-287
Hauptverfasser:	Fletcher, Andrew J. W., Gardner, David S., Edwards, C. Mark B., Fowden, Abigail L., Giussani, Dino A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-Base Equilibrium - physiology Acute Disease Animals Blood Pressure - drug effects Blood Pressure - physiology Carbon Dioxide - blood Catecholamines - blood Chemoreceptor Cells - physiology Dexamethasone - pharmacology Endocrine System - drug effects Endocrine System - physiology Female Fetus - drug effects Fetus - physiology Glucocorticoids - pharmacology Heart Rate, Fetal - drug effects Heart Rate, Fetal - physiology Hypoxia - drug therapy Hypoxia - physiopathology Neuropeptide Y - blood Original Oxygen - blood Pregnancy Regional Blood Flow - drug effects Regional Blood Flow - physiology Sheep Vascular Resistance - drug effects Vascular Resistance - physiology Vasopressins - blood
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