The structure and degradation of aggrecan in human intervertebral disc

The ability of the intervertebral disc to resist compression is dependent on its high proteoglycan concentration. The disc proteoglycans are classified as aggregating or non-aggregating depending on their ability to interact with hyaluronan. The majority of the aggregating proteoglycans are derived...

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Veröffentlicht in:European spine journal 2006-08, Vol.15 Suppl 3 (3), p.S326-332
Hauptverfasser: Roughley, Peter J, Melching, Lee I, Heathfield, Terrence F, Pearce, Richard H, Mort, John S
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Sprache:eng
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