Regulatory effects of Th1‐type (IFN‐γ, IL‐12) and Th2‐type cytokines (IL‐10, IL‐13) on parasite‐specific cellular responsiveness in Onchocerca volvulus‐infected humans and exposed endemic controls

The present study investigated in vitro the regulatory effects of T helper 1 (Th1)‐type (interferon‐γ, IFN‐γ; interleukin‐12, IL‐12) and Th2‐type cytokines (IL‐10, IL‐13) on Onchocerca volvulus‐specific cellular reactivity in onchocerciasis patients, and in exposed endemic control individuals presen...

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Veröffentlicht in:	Immunology 1999-06, Vol.97 (2), p.219-225
Hauptverfasser:	Soboslay, P T, Lüder, C G, Riesch, S, Geiger, S M, Banla, M, Batchassi, E, Stadler, A, Schulz-Key, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged AIDS/HIV Animals Antibodies, Helminth - biosynthesis Antigens, Helminth - immunology Cell Culture Techniques Child Cytokines - immunology Humans Immunity, Cellular Immunoglobulin G - biosynthesis Interferon-gamma - immunology Interleukin-10 - immunology Interleukin-12 - immunology Interleukin-13 - immunology Middle Aged Onchocerca volvulus - immunology Onchocerciasis - immunology Original Phytohemagglutinins - immunology Th1 Cells - immunology Th2 Cells - immunology
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