Endodermal Nodal-related signals and mesoderm induction in Xenopus

In Xenopus, mesoderm induction by endoderm at the blastula stage is well documented, but the molecular nature of the endogenous inductive signals remains unknown. The carboxy-terminal fragment of Cerberus, designated Cer-S, provides a specific secreted antagonist of mesoderm-inducing Xenopus Nodal-R...

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Veröffentlicht in:	Development (Cambridge) 2000-03, Vol.127 (6), p.1173-1183
Hauptverfasser:	Agius, E, Oelgeschläger, M, Wessely, O, Kemp, C, De Robertis, E M
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin protein Animals Base Sequence beta -catenin Blastocyst - cytology Blastocyst - metabolism Cerberus Derriere protein DNA Primers - genetics Embryonic Induction Endoderm Endoderm - cytology Endoderm - metabolism Female Gene Expression Regulation, Developmental Intercellular Signaling Peptides and Proteins Mesoderm - cytology Mesoderm - metabolism Nodal Protein Organizers, Embryonic Proteins - genetics Recombination, Genetic RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction Transforming Growth Factor beta - genetics VegT protein Vg1 protein Xenopus Xenopus - embryology Xenopus - genetics Xenopus - metabolism Xenopus Proteins Xnr protein Xnr1 gene Xnr2 gene Xnr4 gene
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