Inactivation of cleavage factor I components Rna14p and Rna15p induces sequestration of small nucleolar ribonucleoproteins at discrete sites in the nucleus

Small nucleolar RNAs (snoRNAs) associate with specific proteins forming small nucleolar ribonucleoprotein (snoRNP) particles, which are essential for ribosome biogenesis. The snoRNAs are transcribed, processed, and assembled in snoRNPs in the nucleoplasm. Mature particles are then transported to the...

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Veröffentlicht in:	Molecular biology of the cell 2008-04, Vol.19 (4), p.1499-1508
Hauptverfasser:	Carneiro, Tiago, Carvalho, Célia, Braga, José, Rino, José, Milligan, Laura, Tollervey, David, Carmo-Fonseca, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Nucleus - metabolism Genes, Fungal Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism In Situ Hybridization, Fluorescence mRNA Cleavage and Polyadenylation Factors - antagonists & inhibitors mRNA Cleavage and Polyadenylation Factors - genetics mRNA Cleavage and Polyadenylation Factors - metabolism Mutation Nuclear Proteins - genetics Nuclear Proteins - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Ribonucleoproteins, Small Nucleolar - genetics Ribonucleoproteins, Small Nucleolar - metabolism RNA, Fungal - genetics RNA, Fungal - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - antagonists & inhibitors Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism
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