Hypoxia inhibits human recombinant large conductance, Ca2+-activated K+ (maxi-K) channels by a mechanism which is membrane delimited and Ca2+ sensitive
Large conductance, Ca 2+ -activated K + (maxi-K) channel activity was recorded in excised, inside-out patches from HEK 293 cells stably co-expressing the α- and β-subunits of human brain maxi-K channels. At +50 mV, and in the presence of 300 n m , single channel activity was acutely and reversibly...
Gespeichert in:
Veröffentlicht in: | The Journal of physiology 2002-05, Vol.540 (3), p.771-780 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Schreiben Sie den ersten Kommentar!