Autocrine Action of Amphiregulin in a Colon Carcinoma Cell Line and Immunocytochemical Localization of Amphiregulin in Human Colon

Amphiregulin (AR) is a newly discovered glycosylated, 84-amino acid residue polypeptide growth regulator which has sequence homology to the EGF family of proteins. To obtain immunological reagents to study the biological role of AR, two synthetic peptides containing sequences corresponding to distin...

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Veröffentlicht in:	The Journal of cell biology 1992-08, Vol.118 (3), p.741-751
Hauptverfasser:	Johnson, Gibbes R., Saeki, Toshiaki, Gordon, Alfred W., Shoyab, Mohammed, Salomon, David S., Stromberg, Kurt
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphiregulin Analytical, structural and metabolic biochemistry Antibodies Antibodies, Monoclonal - immunology Biological and medical sciences Cancer Carcinoma Cell Division - physiology Cell growth Cell lines Cell nucleus Cells Cellular biology Colon Colon - metabolism Colonic Neoplasms - metabolism Culture Media Delta cells EGF Family of Proteins Epithelial cells ErbB Receptors - metabolism Fundamental and applied biological sciences. Psychology Glycoproteins Glycoproteins - metabolism Glycoproteins - physiology Growth Substances - metabolism Growth Substances - physiology Humans Immunohistochemistry Intercellular Signaling Peptides and Proteins Messenger RNA Precipitin Tests Proteins Receptors RNA, Messenger - genetics Transcription, Genetic Tumor Cells, Cultured
Online-Zugang:	Volltext
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