Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics

Cyclooxygenase (COX) catalysis by prostaglandin H synthase (PGHS) is a key control step for regulation of prostanoid biosynthesis. Both PGHS isoforms are integral membrane proteins and their substrate fatty acids readily partition into membranes, but the impact of phospholipids and lipid membranes o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Prostaglandins & other lipid mediators 2008-03, Vol.85 (3), p.134-143
Hauptverfasser:	Rand Doyen, J., Yucer, Nur, Lichtenberger, Lenard M., Kulmacz, Richard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arachidonic Acid - pharmacology Cyclooxygenase 1 - metabolism Cyclooxygenase 2 - metabolism Cyclooxygenase inhibitors Cyclooxygenase Inhibitors - pharmacology Cyclooxygenase-1 Cyclooxygenase-2 Hydrogen-Ion Concentration Ibuprofen - pharmacology Kinetics Lipid Bilayers - pharmacology Liposomes - pharmacology Membrane Fluidity Micelles Oleic Acid - pharmacology Phosphatidylcholines - pharmacology Phosphatidylserines - pharmacology Phospholipids Phospholipids - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!