HSP20 phosphorylation and interstitial metabolites in hypoxia-induced dilation of swine coronary arteries

Objective: Hypoxia induces coronary artery dilation, but the responsible mechanism is largely unknown. Many stimuli induce arterial smooth muscle relaxation by reducing ser19‐myosin regulatory light chain (MLC) phosphorylation. Other stimuli can induce smooth muscle relaxation without reductions in...

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Veröffentlicht in:	Acta physiologica Scandinavica 2005-05, Vol.184 (1), p.37-44
Hauptverfasser:	Frøbert, O., Buus, C. L., Rembold, C. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Glucose - analysis Blood vessels and receptors Coronary Vessels - drug effects Coronary Vessels - metabolism Dilatation, Pathologic Fundamental and applied biological sciences. Psychology Heat-Shock Proteins - metabolism HSP20 Heat-Shock Proteins hypoxia Hypoxia - metabolism Lactates - blood Male metabolism microdialysis Muscle, Smooth, Vascular - metabolism Myosin Light Chains - metabolism Nitroglycerin - pharmacology Phosphoproteins - metabolism Phosphorylation Pyruvic Acid - blood signal transduction smooth muscle Swine vasodilation Vasodilator Agents - pharmacology Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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