Perturbed desmosomal cadherin expression in grainy head-like 1-null mice

In Drosophila , the grainy head ( grh ) gene plays a range of key developmental roles through the regulation of members of the cadherin gene family. We now report that mice lacking the grh homologue grainy head‐like 1 ( Grhl1 ) exhibit hair and skin phenotypes consistent with a reduction in expressi...

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