Integrating ethics and science in the International HapMap Project
Genomics resources that use samples from identified populations raise scientific, social and ethical issues that are, in many ways, inextricably linked. Scientific decisions about which populations to sample to produce the HapMap, an international genetic variation resource, have raised questions ab...
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| Veröffentlicht in: | Nature reviews. Genetics 2004-06, Vol.5 (6), p.467-475 |
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| container_title | Nature reviews. Genetics |
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| creator | Foster, Morris W |
| description | Genomics resources that use samples from identified populations raise scientific, social and ethical issues that are, in many ways, inextricably linked. Scientific decisions about which populations to sample to produce the HapMap, an international genetic variation resource, have raised questions about the relationships between the social identities used to recruit participants and the biological findings of studies that will use the HapMap. The sometimes problematic implications of those complex relationships have led to questions about how to conduct genetic variation research that uses identified populations in an ethical way, including how to involve members of a population in evaluating the risks and benefits posed for everyone who shares that identity. The ways in which these issues are linked is increasingly drawing the scientific and ethical spheres of genomics research closer together. |
| doi_str_mv | 10.1038/nrg1351 |
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Genome</subject><subject>Genetic Privacy</subject><subject>Genetic Variation</subject><subject>Genome, Human</subject><subject>Genomics - ethics</subject><subject>Haplotypes - genetics</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Informed Consent</subject><subject>International Cooperation</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>opinion-2</subject><subject>Population Groups - classification</subject><subject>Population Groups - genetics</subject><subject>Sampling Studies</subject><issn>1471-0056</issn><issn>1471-0064</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0t2L1DAQAPAiine3iv-BFMVTH_bMR9O0L8J5qLdwovjxHJJ02mbpJmuSHvrfm3XL3fYQJA8NnV9mwmSy7AlGZxjR6o31HaYM38uOccHxEqGyuH-zZ-VRdhLCGiFcYk4fZkeYYUbruj7O3q1shM7LaGyXQ-yNDrm0TR60AashNzaPPeQ75W1Szsohv5TbT3Kbf_FuDTo-yh60cgjwePoush8f3n-_uFxeff64uji_WuqyKuKyrWpSE8XKdF-pqVaqgpqWtGkRUxVvOCWakBTlmGilFQApi0IzBRQr1SK6yN7u825HtYFGg41eDmLrzUb638JJI-YRa3rRuWtBCMc4VVpkp1MC736OEKLYmKBhGKQFNwbBcV0QXpD_QszrmlDEE3x2B67dmPo0hFSUclYwXCT0fI86OYAwtnXpdnqXUZzjqqpYQjips3-otBrYGO0stCb9nx14PTuQTIRfsZNjCGL17evcnh7YHuQQ--CGcfeeYQ5f7qH2LgQP7U17MRK7SRPTpCX59PA1bt00Wgm8mIAMWg6tl1abcOAqVPC_iV7tXUgh24G_7eHdmn8AZmbk5w</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>Foster, Morris W</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20040601</creationdate><title>Integrating ethics and science in the International HapMap Project</title><author>Foster, Morris W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c684t-f89292b56038ac3cbb8e9363df05b87d732c22603712cbcbee2644c5be31bbf03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Agriculture</topic><topic>Animal Genetics and Genomics</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cancer Research</topic><topic>Databases, Genetic</topic><topic>Fundamental and applied biological sciences. 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| ispartof | Nature reviews. Genetics, 2004-06, Vol.5 (6), p.467-475 |
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| subjects | Agriculture Animal Genetics and Genomics Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Databases, Genetic Fundamental and applied biological sciences. Psychology Gene Function Genes. Genome Genetic Privacy Genetic Variation Genome, Human Genomics - ethics Haplotypes - genetics Human Genetics Humans Informed Consent International Cooperation Molecular and cellular biology Molecular genetics opinion-2 Population Groups - classification Population Groups - genetics Sampling Studies |
| title | Integrating ethics and science in the International HapMap Project |
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