Hand transcription factors cooperatively regulate development of the distal midline mesenchyme

Hand proteins are evolutionally conserved basic helix–loop–helix (bHLH) transcription factors implicated in development of neural crest-derived tissues, heart and limb. Hand1 is expressed in the distal (ventral) zone of the branchial arches, whereas the Hand2 expression domain extends ventrolaterall...

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Veröffentlicht in:	Developmental biology 2007-10, Vol.310 (1), p.154-168
Hauptverfasser:	Barbosa, Ana C., Funato, Noriko, Chapman, Shelby, McKee, Marc D., Richardson, James A., Olson, Eric N., Yanagisawa, Hiromi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Helix-Loop-Helix Transcription Factors - physiology Cranofacial DNA-Binding Proteins - physiology Gene Expression Regulation, Developmental Homeodomain Proteins - physiology Incisor Mandible Mesoderm - embryology Mesoderm - physiology Mice Mice, Knockout Morphogenesis Neural crest Neural Crest - embryology Paired Box Transcription Factors - physiology Tooth - embryology
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