Receptor system response kinetics reveal functional subtypes of native murine and recombinant human GABAA receptors

Regional distinctions in GABA type A (GABA A ) miniature IPSC responses are thought to be determined by postsynaptic receptor composition. The kinetics of receptor activation and deactivation were studied using rapid exchange (100 Î¼s) of GABA at excised patches containing recombinant (Î±1Î²1Î³2 or...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of physiology 1999-03, Vol.515 (3), p.711-727
Hauptverfasser:	McClellan, Annette M. L., Twyman, Roy E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cerebral Cortex - cytology Cerebral Cortex - physiology Computer Simulation Embryo, Mammalian gamma-Aminobutyric Acid - pharmacology Humans Kidney Kinetics Macromolecular Substances Membrane Potentials - drug effects Mice Neurons - cytology Neurons - drug effects Neurons - physiology Original Patch-Clamp Techniques Phenotype Receptors, GABA-A - classification Receptors, GABA-A - genetics Receptors, GABA-A - physiology Recombinant Proteins - chemistry Recombinant Proteins - metabolism Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!