Chronic hypoxia enhances the secretory response of rat phaeochromocytoma cells to acute hypoxia

Amperometric recordings were made from individual phaeochromocytoma (PC12) cells using carbon fibre microelectrodes to investigate the effects of chronic hypoxia (10% O 2 ) on the secretory responses evoked by acute hypoxia. Exposure to chronic hypoxia for 21â26 h increased the frequency of exocyt...

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Veröffentlicht in:	The Journal of physiology 1999-01, Vol.514 (2), p.483-491
Hauptverfasser:	Taylor, S. C., Peers, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms - physiopathology Animals Cadmium - pharmacology Calcium - pharmacology Calcium - physiology Calcium Channel Blockers - pharmacology Cations - pharmacology Cell Hypoxia - physiology Electrophysiology Exocytosis Kinetics Original PC12 Cells Pheochromocytoma - physiopathology Potassium Channels - drug effects Potassium Channels - physiology Rats Tetraethylammonium - pharmacology Time Factors
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