Differential Involvement of Enkephalins in Analgesic Tolerance, Locomotor Sensitization, and Conditioned Place Preference Induced by Morphine

In this study, the authors investigated the role of enkephalins in morphine-induced conditioned place preference, locomotor sensitization, and analgesic tolerance. Both preproenkephalin wild type (ppENK [+/+]) and knockout (ppENK [−/−]) mice showed similar preference for the morphine-paired chamber...

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Veröffentlicht in:	Behavioral neuroscience 2006-02, Vol.120 (1), p.10-15
Hauptverfasser:	Marquez, Paul, Baliram, Ramkumarie, Gajawada, Nagaraju, Friedman, Theodore C, Lutfy, Kabirullah
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesic Drugs Analgesics Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacology Animal Animal Locomotion Animals Biological and medical sciences Choice Behavior Conditioning Conditioning (Psychology) - drug effects Drug Tolerance Drug Tolerance - physiology Enkephalins Enkephalins - metabolism Enkephalins - physiology Fundamental and applied biological sciences. Psychology Learning. Memory Locomotion - drug effects Male Mice Mice, Inbred C57BL Mice, Knockout Morphine Morphine - administration & dosage Morphine - pharmacology Motor ability Narcotics Place Conditioning Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Sensitization Spatial Behavior - drug effects
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