An Essential Role for Fibronectin Extra Type III Domain A in Pulmonary Fibrosis

Tissue fibrosis is considered a dysregulated wound-healing response. Fibronectin containing extra type III domain A (EDA) is implicated in the regulation of wound healing. EDA-containing fibronectin is deposited during wound repair, and its presence precedes that of collagen. To investigate the role...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2008-03, Vol.177 (6), p.638-645
Hauptverfasser:	Muro, Andres F, Moretti, Federico A, Moore, Bethany B, Yan, Mei, Atrasz, Rachelle G, Wilke, Carol A, Flaherty, Kevin R, Martinez, Fernando J, Tsui, Jessica L, Sheppard, Dean, Baralle, Francisco E, Toews, Galen B, White, Eric S
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antibodies Biological and medical sciences Cells, Cultured Cloning Collagen Disease Models, Animal E. Interstitial Lung Disease Fibroblasts Fibronectins - chemistry Fibronectins - metabolism Growth factors Humans Intensive care medicine Lavage Lungs Medical sciences Mice Mice, Knockout Pneumology Polymerase chain reaction Pulmonary fibrosis Pulmonary Fibrosis - physiopathology Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Smooth muscle Wound healing Wound Healing - physiology
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