Airway epithelial cell response to human metapneumovirus infection

Abstract Human metapneumovirus (hMPV) is a major cause of lower respiratory tract infections (LRTIs) in infants, elderly and immunocompromised patients. In this study, we show that hMPV can infect in a similar manner epithelial cells representative of different tracts of the airways. hMPV-induced ex...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2007-11, Vol.368 (1), p.91-101
Hauptverfasser:	Bao, X, Liu, T, Spetch, L, Kolli, D, Garofalo, R.P, Casola, A
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Airway epithelial cells Cell Line Chemokines Chemokines - biosynthesis Epithelial Cells - virology hMPV Human metapneumovirus Humans INFANTS Infectious Disease INFLAMMATION INTERFERON Interferon Regulatory Factors - metabolism Interferon-Stimulated Gene Factor 3 - metabolism Metapneumovirus - growth & development Metapneumovirus - immunology NF-kappa B - metabolism PATIENTS Respiratory Mucosa - virology TRANSCRIPTION TRANSCRIPTION FACTORS TRANSDUCERS
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