Autoantibody profile in the experimental model of scleroderma induced by type V human collagen

The aim of this study is to evaluate the humoral autoimmune response in the experimental model of systemic sclerosis (SSc) induced by human type V collagen (huCol V). New Zealand rabbits were immunized with huCol V in Freund's complete adjuvant (FCA) and boosted twice with 15 days intervals wit...

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Veröffentlicht in:	Immunology 2007-09, Vol.122 (1), p.38-46
Hauptverfasser:	Callado, Maria R.M, Viana, Vilma S.T, Vendramini, Margarete B.G, Leon, Elaine P, Bueno, Cleonice, Velosa, Ana P.P, Teodoro, Walcy R, Yoshinari, Natalino H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Antinuclear - blood autoantibodies Autoantibodies - biosynthesis Biomarkers - blood Collagen Type V - immunology Disease Models, Animal DNA Topoisomerases, Type I - immunology Enzyme-Linked Immunosorbent Assay - methods Esophagus - pathology experimental model Female Humans Immunization - methods Lung - pathology Original Rabbits Rheumatoid Factor - blood Scleroderma Scleroderma, Systemic - immunology Scleroderma, Systemic - pathology Skin - pathology systemic sclerosis Type V collagen
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