Synthesis and biological activity of 5-aza-ellipticine derivatives

Novel 5-aza-ellipticine derivatives were synthesized and tested as antitumor agents. The new compounds were prepared more readily than the analogous ellipticine derivatives, which are known to be potent anti-tumor agents Although the novel 5-aza-ellipticine derivatives are not as biologically active...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2007-04, Vol.17 (8), p.2380-2384
Hauptverfasser: Moody, Deborah L., Dyba, Marcin, Kosakowska-Cholody, Teresa, Tarasova, Nadya I., Michejda, Christopher J.
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Sprache:eng
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