The RIIβ Regulatory Subunit of Protein Kinase A Binds to cAMP Response Element: An Alternative cAMP Signaling Pathway
cAMP, through the activation of cAMP-dependent protein kinase (PKA), is involved in transcriptional regulation. In eukaryotic cells, cAMP is not considered to alter the binding affinity of CREB/ATF to cAMP-responsive element (CRE) but to induce serine phosphorylation and consequent increase in trans...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1998-06, Vol.95 (12), p.6687-6692 |
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