Rapid Diagnosis of MEN2B Using Unlabeled Probe Melting Analysis and the LightCycler 480 Instrument

Multiple endocrine neoplasia type 2B (MEN2B) is an autosomal dominant, inherited cancer syndrome. MEN2B patients have a high risk of developing medullary thyroid carcinoma, and prophylactic thyroidectomy is recommended by 6 months of age. Genetic testing can identify MEN2B patients before cancer pro...

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Veröffentlicht in:	The Journal of molecular diagnostics : JMD 2008-03, Vol.10 (2), p.123-128
Hauptverfasser:	Margraf, Rebecca L, Mao, Rong, Wittwer, Carl T
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Probes - metabolism Exons - genetics Genotype Humans Multiple Endocrine Neoplasia Type 2b - diagnosis Nucleic Acid Denaturation Pathology Polymerase Chain Reaction - instrumentation Proto-Oncogene Proteins c-ret - genetics Technical Advances
Online-Zugang:	Volltext
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