The influence of esters and carboxylic acids as the N-substituent of opioids. 1. Benzomorphans
To investigate the effects of carboxylic ester and acid moieties as the N -substituent of opioids, a short series of racemic N -substituted normetazocines was prepared. The introduction of both groups as the normetazocine N -substituent produced compounds which displayed low potency in vitro and in...
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Veröffentlicht in: | Bioorganic & medicinal chemistry 2007-10, Vol.16 (2), p.869-873 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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