The PYRIN domain: A member of the death domain‐fold superfamily

PYRIN domains were identified recently as putative protein–protein interaction domains at the N‐termini of several proteins thought to function in apoptotic and inflammatory signaling pathways. The ∼95 residue PYRIN domains have no statistically significant sequence homology to proteins with known t...

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Veröffentlicht in:	Protein science 2001-09, Vol.10 (9), p.1911-1918
Hauptverfasser:	Fairbrother, Wayne J., Gordon, Nathaniel C., Humke, Eric W., O'Rourke, Karen M., Starovasnik, Melissa A., Yin, Jian‐Ping, Dixit, Vishva M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Apoptosis caspase recruitment domain Circular Dichroism Cytoskeletal Proteins death domain fold recognition For the Record inflammation Models, Molecular Molecular Sequence Data Protein Folding protein modeling Protein Structure, Tertiary Proteins - chemistry Proteins - metabolism Pyrin pyrin domain secondary structure prediction Sequence Alignment Sequence Homology, Amino Acid
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