Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum

The process of mRNA localization typically utilizes cis-targeting elements and trans-recognition factors to direct the compartmental organization of translationally suppressed mRNAs. mRNA localization to the endoplasmic reticulum (ER), in contrast, occurs via a co-translational, signal sequence/sign...

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Veröffentlicht in:	RNA (Cambridge) 2008-03, Vol.14 (3), p.445-453
Hauptverfasser:	Pyhtila, Brook, Zheng, Tianli, Lager, Patrick J, Keene, Jack D, Reedy, Mary C, Nicchitta, Christopher V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Cercopithecus aethiops COS Cells DNA Primers - genetics Endoplasmic Reticulum - metabolism HeLa Cells Humans Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice Oligonucleotide Array Sequence Analysis Protein Biosynthesis RNA, Messenger - genetics RNA, Messenger - metabolism Signal Recognition Particle - genetics Signal Recognition Particle - metabolism Subcellular Fractions - metabolism
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