The logistics of broader pre-clinical evaluation of potential anti-cancer agents with reference to anti-tumour activity and toxicity of mitozolomide

Anti-tumour responses with CCRG81010, M & B 39565, NSC 353451, 8-carbamoyl-3-(2-chloroethyl)imidazo [5,1-d]-1,2,3,5-tetrazin-4(3H)-one (Mitozolomide) in a panel of 4 murine colon tumours of varying growth characteristics and chemosensitivity and a spontaneous murine lymphoma are similar to those...

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Veröffentlicht in:	British journal of cancer 1988-08, Vol.58 (2), p.139-143
Hauptverfasser:	Bibby, MC, Double, JA, Wahed, IA, Hirbawi, N, Baker, TG
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Animals Antineoplastic Agents - therapeutic use Biological and medical sciences Biomedical and Life Sciences Biomedicine Blood Cell Count Cancer Research Colonic Neoplasms - drug therapy Colony-Forming Units Assay Drug Evaluation, Preclinical Drug Resistance Epidemiology experimental-oncology Female Lymphoma - drug therapy Male Medical sciences Mice Mice, Inbred Strains Molecular Medicine Nitrogen Mustard Compounds - therapeutic use Nitrogen Mustard Compounds - toxicity Oncology Oocytes - drug effects Organ Size - drug effects Pharmacology. Drug treatments Sperm Count - drug effects Testis - drug effects
Online-Zugang:	Volltext
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