Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1

Early endosomal antigen 1 (EEA1) is a cytosolic protein that specifically binds to early endosomal membranes where it has a crucial role in the tethering process leading to homotypic endosome fusion. Green fluorescent protein‐tagged EEA1 (EEA1‐GFP) was bound to the endosomal membrane throughout the...

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Veröffentlicht in:	EMBO reports 2008-02, Vol.9 (2), p.171-178
Hauptverfasser:	Bergeland, Trygve, Haugen, Linda, Landsverk, Ole J B, Stenmark, Harald, Bakke, Oddmund
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation, B-Lymphocyte - metabolism Binding sites Cell cycle Cell Cycle - physiology Cell Membrane - metabolism Cellular biology Cytosol - metabolism Dogs EEA1 EMBO06 EMBO20 Endosomes - metabolism Fluorescence Recovery After Photobleaching FRAP fusion Histocompatibility Antigens Class II - metabolism Interphase Kinetics Membrane Proteins - chemistry Membrane Proteins - metabolism Membranes Metaphase Molecular biology Phosphatidylinositol Phosphates - metabolism photoactivation Photobleaching Protein Structure, Tertiary Proteins rab5 GTP-Binding Proteins - metabolism Recombinant Fusion Proteins - metabolism Scientific Report Vesicular Transport Proteins - chemistry Vesicular Transport Proteins - metabolism
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