MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

Adhesion molecules expressed by activated endothelial cells play a key role in regulating leukocyte trafficking to sites of inflammation. Resting endothelial cells normally do not express adhesion molecules, but cytokines activate endothelial cells to express adhesion molecules such as vascular cell...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-02, Vol.105 (5), p.1516-1521
Hauptverfasser:	Harris, Tamia A, Yamakuchi, Munekazu, Ferlito, Marcella, Mendell, Joshua T, Lowenstein, Charles J
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological Sciences Cell adhesion & migration Cell Adhesion - genetics Cells Down-Regulation Endothelial cells Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Gene expression Gene Expression Regulation HEK293 cells Human umbilical vein endothelial cells Humans Leukocytes Leukocytes - immunology Messenger RNA MicroRNA MicroRNAs - antagonists & inhibitors MicroRNAs - genetics MicroRNAs - physiology Molecules Oligonucleotides RNA RNA, Antisense - pharmacology Vascular Cell Adhesion Molecule-1 - genetics
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