Interaction of platelet-activating factor, spleen and atrial natriuretic peptide in plasma volume regulation during endotoxaemia in rats

We studied endotoxin (lipopolysaccharide, LPS)-induced platelet-activating factor (PAF) production in various visceral organs, and the effect of PAF antagonists or splenectomy on LPS-induced changes. PAF production in response to LPS was highest in the spleen, followed by ileum, heart, lung and kidn...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of physiology 1998-10, Vol.512 (1), p.227-234
Hauptverfasser:	Qu, Xiao‐Wu, Rozenfeld, Ranna A., Huang, Wei, Crawford, Susan E., Gonzalez‐Crussi, F., Hsueh, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atrial Natriuretic Factor - biosynthesis Atrial Natriuretic Factor - blood Atrial Natriuretic Factor - physiology Blood Pressure - drug effects Endotoxemia - physiopathology Endotoxins - toxicity Homeostasis Lipopolysaccharides - toxicity Male Organ Specificity Original Plasma Volume - drug effects Plasma Volume - physiology Platelet Activating Factor - biosynthesis Platelet Activating Factor - physiology Rats Rats, Sprague-Dawley Spleen - drug effects Spleen - metabolism Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!