Effect of sodium perturbations on rat chemoreceptor spike generation: implications for a Poisson model

The sensitivity of arterial chemoreceptor spike generation to reductions in excitability was examined using rat chemoreceptors in vitro. Axonal excitability was reduced by reducing extracellular sodium concentration ([Na + ] o ) by 10-40 % or by applying low doses of tetrodotoxin (TTX). In normoxia...

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