[K+] dependence of polyamine-induced rectification in inward rectifier potassium channels (IRK1, Kir2.1)

The effects of permeant (K+) ions on polyamine (PA)-induced rectification of cloned strong inwardly rectifying channels (IRK1, Kir2.1) expressed in Xenopus oocytes were examined using patch-clamp techniques. The kinetics of PA-induced rectification depend strongly on external, but not internal, K+ c...

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Veröffentlicht in:	The Journal of general physiology 1996-08, Vol.108 (2), p.105-113
Hauptverfasser:	Lopatin, A N, Nichols, C G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Cellular biology Electrophysiology Membrane Potentials - drug effects Membrane Potentials - physiology Oocytes Patch-Clamp Techniques Polyamines - pharmacology Potassium Potassium - pharmacology Potassium Channels - drug effects Potassium Channels - physiology Potassium Channels, Inwardly Rectifying Xenopus
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