Changes in hippocampal function of ovariectomized rats after sequential low doses of estradiol to simulate the preovulatory estrogen surge

In adult female rats, robust hippocampal changes occur when estradiol rises on the morning of proestrus. Whether estradiol mediates these changes, however, remains unknown. To address this issue, we used sequential injections of estradiol to simulate two key components of the preovulatory surge: the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The European journal of neuroscience 2007-11, Vol.26 (9), p.2595-2612
Hauptverfasser:	Scharfman, Helen E., Hintz, Tana M., Gomez, Juan, Stormes, Kerry A., Barouk, Sharon, Malthankar-Phatak, Gauri H., McCloskey, Daniel P., Luine, Victoria N., MacLusky, Neil J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - physiology Animals BDNF Brain-Derived Neurotrophic Factor - drug effects Brain-Derived Neurotrophic Factor - metabolism Diestrus - drug effects Diestrus - metabolism Dose-Response Relationship, Drug Estradiol - pharmacology estrous cycle Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Female Hippocampus - drug effects Hippocampus - metabolism Learning - drug effects Learning - physiology mossy fibers Mossy Fibers, Hippocampal - drug effects Mossy Fibers, Hippocampal - metabolism Neural Pathways - drug effects Neural Pathways - physiology Neurons - drug effects Neurons - metabolism object placement object recognition Organ Culture Techniques Ovariectomy Ovulation - drug effects Ovulation - physiology potentiation proestrus Proestrus - drug effects Proestrus - metabolism Rats Rats, Sprague-Dawley Synaptic Transmission - drug effects Synaptic Transmission - physiology Time
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!