TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma

In this study, we report on the distribution of tissue inhibitor of matrix metalloproteinase-3 (TIMP-3) mRNA expression in human normal colorectal mucosa, adenomas and adenocarcinomas. Northern blot analysis showed five TIMP-3 mRNA transcripts to be present in normal mucosal epithelium and in modera...

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Veröffentlicht in:	British journal of cancer 1997-06, Vol.75 (11), p.1678-1683
Hauptverfasser:	Powe, DG, Brough, JL, Carter, GI, Bailey, EM, Stetler-Stevenson, WG, Turner, DR, Hewitt, RE
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Biological and medical sciences Biomedical and Life Sciences Biomedicine Blotting, Northern Cancer Research clinical-oncology Colorectal Neoplasms - metabolism Drug Resistance Epidemiology Gastroenterology. Liver. Pancreas. Abdomen Humans In Situ Hybridization Medical sciences Molecular Medicine Oncology Protease Inhibitors - metabolism Proteins - genetics RNA, Messenger - analysis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tissue Inhibitor of Metalloproteinase-3 Tumors
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