Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism

A potential role for sialic acid in the voltage-dependent gating of rat skeletal muscle sodium channels (rSkM1) was investigated using Chinese hamster ovary (CHO) cells stably transfected with rSkM1. Changes in the voltage dependence of channel gating were observed after enzymatic (neuraminidase) re...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of general physiology 1997-03, Vol.109 (3), p.327-343
Hauptverfasser:	Bennett, E, Urcan, M S, Tinkle, S S, Koszowski, A G, Levinson, S R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Biochemistry Blotting, Southern CHO Cells Cricetinae Electrophysiology Genetic Vectors Immunohistochemistry Ion Channel Gating - physiology Ions Membrane Potentials - physiology Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscle, Skeletal - physiology Mutation - physiology Patch-Clamp Techniques Rats Rodents Sequence Deletion - physiology Sialic Acids - chemistry Sialic Acids - physiology Sodium Channels - physiology Transfection - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!