syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

Mannose 6-phosphate receptors (MPRs) are transported from endosomes to the Golgi after delivering lysosomal enzymes to the endocytic pathway. This process requires Rab9 guanosine triphosphatase (GTPase) and the putative tether GCC185. We show in human cells that a soluble NSF attachment protein rece...

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Veröffentlicht in:	The Journal of cell biology 2008-01, Vol.180 (1), p.159-172
Hauptverfasser:	Ganley, Ian G, Espinosa, Eric, Pfeffer, Suzanne R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Binding, Competitive Biochemistry Cell Line Cells Cholera Cholera Toxin - metabolism Chromosomes Endosomes Endosomes - metabolism Enzymes HeLa cells Humans Membrane Glycoproteins - metabolism Membrane Proteins - metabolism Protein Transport - physiology Proteins Qa-SNARE Proteins - genetics Qa-SNARE Proteins - metabolism Qa-SNARE Proteins - physiology rab GTP-Binding Proteins - metabolism Receptor, IGF Type 2 - metabolism Receptors Recycling Small interfering RNA SNARE proteins SNARE Proteins - physiology Syntaxin 16 - metabolism Syntaxin 16 - physiology Toxins trans-Golgi Network - metabolism
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