Protein detection via direct enzymatic amplification of short DNA aptamers

Aptamers are single-stranded nucleic acids that fold into defined tertiary structures to bind target molecules with high specificities and affinities. DNA aptamers have garnered much interest as recognition elements for biodetection and diagnostic applications due to their small size, ease of discov...

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Veröffentlicht in:	Analytical biochemistry 2008-02, Vol.373 (1), p.121-128
Hauptverfasser:	Fischer, Nicholas O., Tarasow, Theodore M., Tok, Jeffrey B.-H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers Aptamers, Nucleotide - chemistry Base Sequence DNA Primers Enzymes - chemistry Limit of detection PCR Polymerase Chain Reaction Proteins - analysis Rolling circle amplification
Online-Zugang:	Volltext
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