A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis

The triggering receptor expressed on myeloid cells (TREM)-1 is a recently discovered receptor expressed on the surface of neutrophils and a subset of monocytes. Engagement of TREM-1 has been reported to trigger the synthesis of proinflammatory cytokines in the presence of microbial products. Previou...

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Veröffentlicht in:	The Journal of experimental medicine 2004-12, Vol.200 (11), p.1419-1426
Hauptverfasser:	Gibot, Sébastien, Kolopp-Sarda, Marie-Nathalie, Béné, Marie-C, Bollaert, Pierre-Edouard, Lozniewski, Alain, Mory, Françoise, Levy, Bruno, Faure, Gilbert C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cells, Cultured Cytokines - biosynthesis Endotoxemia - therapy Humans Inflammation - immunology Inflammation - prevention & control Lipopolysaccharides - toxicity Male Membrane Glycoproteins - blood Membrane Glycoproteins - physiology Mice Mice, Inbred BALB C Molecular Sequence Data NF-kappa B - metabolism Peptide Fragments - pharmacology Receptors, Immunologic - blood Receptors, Immunologic - physiology Sepsis - immunology Sepsis - therapy Triggering Receptor Expressed on Myeloid Cells-1
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