Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is associated with premature and accelerated atherosclerosis. Circulating progenitor cells (CPCs) are circulating bone-marrow derived cells that play an important role in the repair of vascular damage that underlies the development of atherosclerosis. The objective...

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Veröffentlicht in:	Arthritis research & therapy 2007-01, Vol.9 (4), p.R84-R84, Article R84
Hauptverfasser:	Moonen, Jan Renier A J, de Leeuw, Karina, van Seijen, Xavier J Gallego Y, Kallenberg, Cees G M, van Luyn, Marja J A, Bijl, Marc, Harmsen, Martin C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis Atherosclerosis Caspase 8 - genetics Caspase 8 - metabolism Cell Count Cell Proliferation Cells, Cultured Chemotaxis Colony-Forming Units Assay Complications and side effects Endothelium, Vascular - enzymology Endothelium, Vascular - pathology Female Flow Cytometry Gene Expression Health aspects Hematopoietic stem cells Hematopoietic Stem Cells - enzymology Hematopoietic Stem Cells - pathology Humans Leukocytes, Mononuclear - cytology Lupus erythematosus Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - pathology Lupus Erythematosus, Systemic - physiopathology Middle Aged Risk factors RNA, Messenger - metabolism Severity of Illness Index
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