Prenatal PCB Exposure and Thymus Size at Birth in Neonates in Eastern Slovakia

BACKGROUND: Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants, for which animal studies demonstrate immunotoxic effects, including thymic atrophy and suppressed immune responses; human investigations of similar end points are sparse. The thymus is essential for the differentiat...

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Veröffentlicht in:	Environmental health perspectives 2008-01, Vol.116 (1), p.104-109
Hauptverfasser:	Park, Hye-Youn, Hertz-Picciotto, Irva, Petrik, Jan, Palkovicova, Lubica, Kocan, Anton, Trnovec, Tomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alcohol drinking Birth defects Birth weight Chemical hazards Children's Health Environmental Pollutants - blood Environmental Pollutants - toxicity Female Health aspects Humans Immunologic diseases Infant, Newborn Infants Linear regression Maternal Exposure - adverse effects Organ Size - drug effects Polychlorinated biphenyls Polychlorinated Biphenyls - blood Polychlorinated Biphenyls - toxicity Pregnancy Radiology Regression analysis Risk factors Slovakia Thymocytes Thymus Gland - drug effects Thymus Gland - growth & development
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