Enhancer Complexes Located Downstream of Both Human Immunoglobulin Cα Genes

To investigate regulation of human immunoglobulin heavy chain expression, we have cloned DNA downstream from the two human Cα genes, corresponding to the position in the mouse IgH cluster of a locus control region (LCR) that includes an enhancer which regulates isotype switching. Within 25 kb downst...

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Veröffentlicht in:The Journal of experimental medicine 1997-09, Vol.186 (6), p.845-858
Hauptverfasser: Mills, Frederick C., Harindranath, Nagaradona, Mitchell, Mary, Max, Edward E.
Format: Artikel
Sprache:eng
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