Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative

We tested for antigen recognition and T cell receptor (TCR)-ligand binding 12 peptide derivative variants on seven H-2Kd-restricted cytotoxic T lymphocytes (CTL) clones specific for a bifunctional photoreactive derivative of the Plasmodium berghei circumsporozoite peptide 252-260 (SYIPSAEKI). The de...

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Veröffentlicht in:	The Journal of experimental medicine 1997-02, Vol.185 (4), p.629-640
Hauptverfasser:	Kessler, B M, Bassanini, P, Cerottini, J C, Luescher, I F
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Labels AIDS/HIV Amino Acid Sequence CD8-Positive T-Lymphocytes Cell Line Clone Cells fas Receptor - immunology H-2 Antigens - immunology Membrane Glycoproteins - immunology Molecular Sequence Data Peptides - chemistry Peptides - immunology Perforin Pore Forming Cytotoxic Proteins Receptors, Antigen, T-Cell - antagonists & inhibitors Receptors, Antigen, T-Cell - immunology Receptors, Antigen, T-Cell - metabolism T-Lymphocytes, Cytotoxic - immunology
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