How sugars convey information on protein conformation in the endoplasmic reticulum

The N-glycan-dependent quality control of glycoprotein folding prevents endoplasmic reticulum to Golgi exit of folding intermediates, irreparably misfolded glycoproteins and not completely assembled multimeric complexes. It also enhances folding efficiency by preventing aggregation and facilitating...

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Veröffentlicht in:	Seminars in cell & developmental biology 2007-12, Vol.18 (6), p.732-742
Hauptverfasser:	Caramelo, Julio J., Parodi, Armando J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrates - physiology Endoplasmic reticulum Glucosyltransferase Glycoprotein folding Glycoproteins - chemistry Glycoproteins - metabolism Glycosylation Lectins Polysaccharides Protein Folding Quality control
Online-Zugang:	Volltext
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