NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14 i NKT Cells

A defect in RelB, a member of the Rel/nuclear factor (NF)-κB family of transcription factors, affects antigen presenting cells and the formation of lymphoid organs, but its role in T lymphocyte differentiation is not well characterized. Here, we show that RelB deficiency in mice leads to a selective...

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Veröffentlicht in:The Journal of experimental medicine 2003-06, Vol.197 (12), p.1623-1633
Hauptverfasser: Elewaut, Dirk, Shaikh, Raziya B., Hammond, Kirsten J. L., De Winter, Hilde, Leishman, Andrew J., Sidobre, Stephane, Turovskaya, Olga, Prigozy, Theodore I., Ma, Lisa, Banks, Theresa A., Lo, David, Ware, Carl F., Cheroutre, Hilde, Kronenberg, Mitchell
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Sprache:eng
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